منابع مشابه
Leukodepleted-ABO-identical blood components in the treatment of hematologic malignancies: a cost analysis.
To assess the effect of ABO-identical, filtration leukodepleted transfusions on resource consumption and costs of care we performed a cohort study in consecutive adult patients admitted for induction therapy of acute myeloid or lymphoid leukemia during 1985-92 (n = 120) and consecutive adult patients admitted for autologous bone marrow transplantation for Hodgkin's or non-Hodgkin's lymphoma dur...
متن کاملMicrocirculatory effects of the transfusion of leukodepleted or non-leukodepleted red blood cells in patients with sepsis: a pilot study
INTRODUCTION Microvascular alterations impair tissue oxygenation during sepsis. A red blood cell (RBC) transfusion increases oxygen (O2) delivery but rarely improves tissue O2 uptake in patients with sepsis. Possible causes include RBC alterations due to prolonged storage or residual leukocyte-derived inflammatory mediators. The aim of this study was to compare the effects of two types of trans...
متن کاملLeukodepleted versus nonleukodepleted red blood cell transfusion in septic patients: a microcirculatory vision
Storage time and residual leukocytes in red blood cell (RBC) units may be deleterious by increasing the accumulation of leukocyte-derived cytokines and by raising the adhesion of RBCs to endothelium. Leukodepleted RBC transfusion may reduce the incidence of infection and organ dysfunction. However, the influence of leukodepletion on microcirculation remains not well defined in ICU patients. In ...
متن کاملTime Dependent Assessment of Morphological Changes: Leukodepleted Packed Red Blood Cells Stored in SAGM
Usually packed red blood cells (pRBCs) require specific conditions in storage procedures to ensure the maximum shelf life of up to 42 days in 2-6°C. However, molecular and biochemical consequences can affect the stored blood cells; these changes are collectively labeled as storage lesions. In this study, the effect of prolonged storage was assessed through investigating morphological changes an...
متن کاملLeukocytes in blood transfusion: adverse effects and their prevention.
Leukocyte contamination during blood transfusion can cause many adverse effects, such as the transmission of cell-associated infectious agents, febrile non-haemolytic reactions, graft-versus-host disease, and immunosuppression. While using leukodepleted blood components can minimise some of these adverse effects, the leukodepletion of all cellular blood components is costly. A more cost-effecti...
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ژورنال
عنوان ژورنال: Anaesthesia and Intensive Care
سال: 1993
ISSN: 0310-057X,1448-0271
DOI: 10.1177/0310057x9302100111